Which science field has the most promising future?

Computer science
Aerospace engineering
Ecology, resource saving

What is the mankind's most dangerous invention?

Atomic bomb
Fast food

Novosibirsk scientists discover new multiple sclerosis diagnostics

Russian scientists have developed what is believed to be a “simple and efficient” method to diagnose multiple sclerosis, a disease that has had no reliable and affordable diagnostics technique so far, Russian news agency RIA Novosti reported, citing a publication in Analytical Chemistry.

The new method comes from a group of researchers working at a number of Novosibirsk-based institutes run by the Siberian branch of the Russian Academy of Sciences.

Multiple sclerosis (MS) is a chronic autoimmune disease that affects the nerves of the brain and the spinal cord. In such patients, their own immune system destroys myelin, a dielectric biomaterial that insulates the axon of the neuron. Without myelin, nerves fail to conduct signals properly, which leads to motor, visual and sensor problems and brain disorders. The disease is currently considered incurable.

At the moment, MS diagnostics requires a whole range of examinations, including MRI and cerebrospinal fluid (CSF) analysis. None of these has proved 100% reliable when applied separately, and the entire combination is financially prohibitive for many patients and takes a lot of time.

Scientists led by Georgy Nevinsky of the Novosibirsk-based Institute of Chemical Biology and Fundamental Medicine found that multiple sclerosis patients generate special autoimmune antibodies, including those to myelin-associated proteins. “The presence of such antibodies is now viewed as a typical MS characteristic,” the researchers wrote in their publication.

They have synthesized specially designed molecules and ‘attached’ to those the molecules of obelin, a photoprotein. When such a complex molecule runs into an MS-typical antibody, the bioluminescent protein emits a quantum of light, and all scientists have to do is register the emission, the developers described.

The researchers underscore that their new method is simple and highly sensitive. However, it will require a wide variety of tests before regulators approve it for clinical use. 

2014-03-11, Marchmont News.

Keywords: medicine and healthcare, science, Novosibirsk Region

Scientists Revive Ancient Virus Frozen in Siberian Permafrost
Novosibirsk scientists discover new multiple sclerosis diagnostics
Vladivostok team knows how to spare living cells in experiments
Genetics and reproductive health project announced in Russia
NASA to Coldly Go Where No Man Has Gone Before
Construction planned for super-laser more powerful than the Sun
InvesMed conference: Where Investors and Medical Innovations Meet
Government helps Novosibirsk team to seek new cancer therapies
Google developing contact lens device to help people with diabetes monitor blood glucose levels
Researchers Harness Sun's Energy During Day for Use at Night
Nizhny Novgorod to have youth “science techno-city” with submarines and hydrofoils
Startup offers Russians affordable genome testing
Russian analog of DARPA will open by year-end – Russian Government
Fastlane, Prostor and Runa merge assets to create online health and medicine leader
Scientists develop human-on-a-chip to research chemical warfare agent exposure

Leave your comment
Sign up
Enter verification codeEnter verification code

Second Moscow International Foreign Investment Forum
Most popular news
Annual Investment Meeting 2013

Welcome to Investment. Innovation. Business Web Portal – a community-driven platform for all the participants of the investment process both in Russia and abroad!

We work to provide online information exchange between Russian and global investors and innovators, business owners and developers.